Biofreeze is a cryogel, which uses cold therapy to give fast, topical relief from pain associated with: Sports injuries, aching joints and arthritis, back and neck pain, stiff and aching muscles. Biofreeze is the only analgesic containing ILEX, which works by dramatically cooling the affected areas, achieving pain relief in two ways: By reducing blood supply to the area and by reducing the ability of the nerve to conduct pain stimuli. Biofreeze fully penetrates joints and muscles in three minutes and gives effective pain relief for hours - without pills. Maximum benefit will be felt after 2 - 3 applications.